a randomized trial to evaluate the effect of local endometrial injury on the clinical pregnancy rate of frozen embryo transfer cycles in patients with repeated implantation failure
نویسندگان
چکیده
objective: repeated implantation failure (rif) is a condition in which the embryos implantation decreases in the endometrium. so, our aim was to evaluate the effect of local endometrial injury on embryo transfer results. materials and methods: in this simple randomized clinical trial (rct), a total of 120 patients were selected. the participants were less than 40 years old, and they are in their minimum two cycles of vitro fertilization (ivf). patients were divided randomly into two groups of lei (local endometrial injury) and a control group (n = 60 in each group). the first group had four small endometrial injuries from anterior, posterior, and lateral uterus walls which were obtained from people who were in 21 th day of their previous ivf cycle. the second group was the patients who have not received any intervention. results: the experimental and control patients were matched in the following factors. regarding the clinical pregnancy rate, there was no significant difference noted between the experimental and the control group. conclusion: local endometrial injury in a preceding cycle does not increase the clinical pregnancy rate in the subsequent fet cycle of patients with repeated implantation failure.
منابع مشابه
A Randomized Trial to Evaluate the Effect of Local Endometrial Injury on the Clinical Pregnancy Rate of Frozen Embryo Transfer Cycles in Patients With Repeated Implantation Failure
Objective: Repeated implantation failure (RIF) is a condition in which the embryos implantation decreases in the endometrium. So, our aim was to evaluate the effect of local endometrial injury on embryo transfer results. Materials and methods: In this simple randomized clinical trial (RCT), a total of 120 patients were selected. The participants were less than 40 years old, and they are in thei...
متن کاملthe effect of endometrial injury on pregnancy rate in frozen-thawed embryo transfer: a randomized control trial
background: implantation failure is one of the most important factors limiting success in ivf treatment. the majority of trials have demonstrated favorable effect of endometrial injury on implantation success rate especially in women with recurrent implantation failure, while some studies failed to detect any benefit. objective: the purpose of our trial was to explore whether endometrial injury...
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P-191: A Comparison of The Effects of Transdermal Estradiol and Estradiol Valerate on Endometrial Receptivity in Frozen-Thawed Embryo Transfer Cycles: A Randomized Clinical Trial
Background: The aim of this prospective randomized clinical trial was to determine the optimal endometrial preparation protocol by comparing the clinical outcome of two methods of endometrial preparation in FET cycles, that is, oral estradiol and 17 β-estradiol transdermal patch. Materials and Methods: A total number of 90 patients were scheduled for FET. In the study group (n=45), 17-B estradi...
متن کاملThe effect of endometrial injury on pregnancy rate in frozen-thawed embryo transfer: A randomized control trial
BACKGROUND Implantation failure is one of the most important factors limiting success in IVF treatment. The majority of trials have demonstrated favorable effect of endometrial injury on implantation success rate especially in women with recurrent implantation failure, while some studies failed to detect any benefit. OBJECTIVE The purpose of our trial was to explore whether endometrial injury...
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عنوان ژورنال:
journal of family and reproductive healthجلد ۱۰، شماره ۳، صفحات ۱۰۸-۱۱۴
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